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Tissue: HT-29
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ABCC3/17:50678211-50678213-50678045-50678047-+/+ ABCC3 protein_coding +/+ interior 17:50678211-50678045 166.0 Human
ABCC3/17:50678216-50678219-50677740-50677743-+/+ ABCC3 protein_coding +/+ canonical (exon-exon) 17:50678219-50677743 476.0 Human
ABCC4/13:95034606-95034609-95053186-95053189--/- ABCC4 protein_coding -/- partial 13:95034606-95053186 18580.0 Human
ABCC4/13:95161191-95161195-95166370-95166374--/- ABCC4 protein_coding -/- interior 13:95161191-95166370 5179.0 Human
ABCC4/13:95243406-95243410-95243601-95243605--/- ABCC4 protein_coding -/- interior 13:95243406-95243601 195.0 Human
ABCD1/X:153730530-153730536-153729976-153729982-+/+ ABCD1 protein_coding +/+ interior X:153730530-153729976 554.0 Human
ABCD3/1:94463100-94463108-94462966-94462974-+/+ ABCD3 protein_coding +/+ interior 1:94463100-94462966 134.0 Human
ABCF2-H2BK1/7:151213709-151213712-151213933-151213936--/- ABCF2-H2BK1 protein_coding -/- interior 7:151213709-151213933 224.0 Human
ABCF2-H2BK1/7:151219107-151219108-151226358-151226359--/- ABCF2-H2BK1 protein_coding -/- interior 7:151219107-151226358 7251.0 Human
ABHD11/7:73736487-73736488-73736619-73736620--/- ABHD11 protein_coding -/- interior 7:73736487-73736619 132.0 Human