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Tissue: breast epithelium
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
A2M/12:9094973-9094976-9095701-9095704--/- A2M protein_coding -/- canonical (exon-exon) 12:9094973-9095701 728.0 Human
A2M/12:9095610-9095612-9101534-9101536--/- A2M protein_coding -/- interior 12:9095612-9101536 5924.0 Human
A2M/12:9112370-9112375-9113411-9113416--/- A2M protein_coding -/- interior 12:9112375-9113416 1041.0 Human
AAMP/2:218264237-218264238-218264531-218264532--/- AAMP protein_coding -/- interior 2:218264238-218264532 294.0 Human
ABCA1/9:104923874-104923875-104923998-104923999--/- ABCA1 protein_coding -/- interior 9:104923874-104923998 124.0 Human
ABCA11P/4:442561-442566-442729-442734--/- ABCA11P transcribed_processed_pseudogene -/- interior 4:442561-442729 168.0 Human
ABCA5/17:69320949-69320950-69321327-69321328--/- ABCA5 protein_coding -/- interior 17:69320950-69321328 378.0 Human
ABCA9/17:68975125-68975127-68975283-68975285--/- ABCA9 protein_coding -/- interior 17:68975125-68975283 158.0 Human
ABCD3/1:94480604-94480609-94455730-94455735-+/+ ABCD3 protein_coding +/+ partial 1:94480604-94455730 24874.0 Human
ABLIM1/10:114434373-114434381-114435204-114435212--/- ABLIM1 protein_coding -/- interior 10:114434381-114435212 831.0 Human