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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
intergenic/11:124263727-124263741-124264185-124264199--/. intergenic Na -/. intergenic 11:124263727-124264185 458.0 Crab-eating macaque
MYL12B/18:63754731-63754735-63733028-63733032-+/+ MYL12B protein_coding +/+ canonical (exon-exon) 18:63754731-63733028 21703.0 Crab-eating macaque
intergenic/11:124263994-124264013-124264678-124264697--/. intergenic Na -/. intergenic 11:124264012-124264696 684.0 Crab-eating macaque
intergenic/11:124264842-124264847-124263700-124263705-+/. intergenic Na +/. intergenic 11:124264842-124263700 1142.0 Crab-eating macaque
intergenic/11:124264527-124264537-124264983-124264993--/. intergenic Na -/. intergenic 11:124264537-124264993 456.0 Crab-eating macaque
MYL12B/18:63733028-63733032-63754731-63754735--/+ MYL12B protein_coding -/+ antisense 18:63733032-63754735 21703.0 Crab-eating macaque
intergenic/11:124264521-124264523-124264293-124264295-+/. intergenic Na +/. intergenic 11:124264521-124264293 228.0 Crab-eating macaque
intergenic/11:124263955-124263969-124264185-124264199--/. intergenic Na -/. intergenic 11:124263967-124264197 230.0 Crab-eating macaque
intergenic/11:124264906-124264913-124263994-124264001-+/. intergenic Na +/. intergenic 11:124264911-124263999 912.0 Crab-eating macaque
intergenic/11:124264293-124264295-124264521-124264523--/. intergenic Na -/. intergenic 11:124264293-124264521 228.0 Crab-eating macaque