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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
MYL12B/18:63730737-63730745-63750032-63750040--/+ MYL12B protein_coding -/+ antisense 18:63730744-63750039 19295.0 Crab-eating macaque
GSTM5/1:113902534-113902535-113918959-113918960--/- GSTM5 protein_coding -/- partial 1:113902535-113918960 16425.0 Crab-eating macaque
PIGL/16:16159833-16159835-16160061-16160063--/- PIGL protein_coding -/- interior 16:16159835-16160063 228.0 Crab-eating macaque
intergenic/11:124264983-124264993-124264527-124264537-+/. intergenic Na +/. intergenic 11:124264983-124264527 456.0 Crab-eating macaque
intergenic/11:124264185-124264199-124264641-124264655--/. intergenic Na -/. intergenic 11:124264186-124264642 456.0 Crab-eating macaque
intergenic/11:124264983-124264993-124263841-124263851-+/. intergenic Na +/. intergenic 11:124264983-124263841 1142.0 Crab-eating macaque
intergenic/11:124264983-124264993-124263613-124263623-+/. intergenic Na +/. intergenic 11:124264993-124263623 1370.0 Crab-eating macaque
intergenic/11:124264392-124264412-124264620-124264640--/. intergenic Na -/. intergenic 11:124264405-124264633 228.0 Crab-eating macaque
intergenic/11:124264983-124264993-124264299-124264309-+/. intergenic Na +/. intergenic 11:124264993-124264309 684.0 Crab-eating macaque
CAPZB/1:205130593-205130597-205149570-205149574--/+ CAPZB protein_coding -/+ antisense 1:205130597-205149574 18977.0 Crab-eating macaque