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Tissue: breast epithelium
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ACTB/7:5528500-5528503-5529630-5529633--/- ACTB protein_coding -/- interior 7:5528503-5529633 1130.0 Human
ACTB/7:5528509-5528518-5529334-5529343--/- ACTB protein_coding -/- interior 7:5528509-5529334 825.0 Human
ACTB/7:5528555-5528557-5529599-5529601--/- ACTB protein_coding -/- interior 7:5528555-5529599 1044.0 Human
ACTB/7:5528563-5528564-5528708-5528709--/- ACTB protein_coding -/- partial 7:5528563-5528708 145.0 Human
ACTB/7:5528570-5528570-5528840-5528840--/- ACTB protein_coding -/- interior 7:5528570-5528840 270.0 Human
ACTB/7:5528775-5528779-5529102-5529106--/- ACTB protein_coding -/- interior 7:5528779-5529106 327.0 Human
ACTB/7:5529165-5529168-5529565-5529568--/- ACTB protein_coding -/- interior 7:5529165-5529565 400.0 Human
ACTG1/17:81509985-81509987-81510510-81510512--/- ACTG1 protein_coding -/- interior 17:81509985-81510510 525.0 Human
ACTG1/17:81510042-81510043-81510295-81510296--/- ACTG1 protein_coding -/- interior 17:81510042-81510295 253.0 Human
ACTG1/17:81510268-81510269-81510650-81510651--/- ACTG1 protein_coding -/- interior 17:81510269-81510651 382.0 Human