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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
intergenic/11:124264994-124265006-124264766-124264778-+/. intergenic Na +/. intergenic 11:124265006-124264778 228.0 Crab-eating macaque
intergenic/11:124264734-124264754-124263820-124263840-+/. intergenic Na +/. intergenic 11:124264734-124263820 914.0 Crab-eating macaque
intergenic/11:124263706-124263726-124264848-124264868--/. intergenic Na -/. intergenic 11:124263726-124264868 1142.0 Crab-eating macaque
FAHD2A/13:450669-450673-470528-470532--/+ FAHD2A protein_coding -/+ antisense 13:450673-470532 19859.0 Crab-eating macaque
intergenic/11:124264797-124264799-124264113-124264115-+/. intergenic Na +/. intergenic 11:124264799-124264115 684.0 Crab-eating macaque
intergenic::CCDC127/6:348287-348289-305206-305208-+/- intergenic::CCDC127 protein_coding +/- intergenic 6:348287-305206 43081.0 Crab-eating macaque
intergenic/11:124264200-124264220-124264884-124264904--/. intergenic Na -/. intergenic 11:124264220-124264904 684.0 Crab-eating macaque
intergenic/11:124264980-124264993-124264752-124264765-+/. intergenic Na +/. intergenic 11:124264993-124264765 228.0 Crab-eating macaque
UBB/16:16160154-16160171-16159698-16159715-+/- UBB protein_coding +/- antisense 16:16160171-16159715 456.0 Crab-eating macaque
intergenic/11:124264200-124264208-124265112-124265120--/. intergenic Na -/. intergenic 11:124264208-124265120 912.0 Crab-eating macaque