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Tissue: breast epithelium
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ACTG1/17:81510589-81510591-81511489-81511491--/- ACTG1 protein_coding -/- interior 17:81510591-81511491 900.0 Human
ACTG1/17:81510707-81510713-81511469-81511475--/- ACTG1 protein_coding -/- interior 17:81510713-81511475 762.0 Human
ACTG1/17:81511181-81511182-81511529-81511530--/- ACTG1 protein_coding -/- interior 17:81511182-81511530 348.0 Human
ACTG1/17:81511236-81511241-81511997-81512002--/- ACTG1 protein_coding -/- interior 17:81511241-81512002 761.0 Human
ACTG1/17:81511495-81511496-81512092-81512093--/- ACTG1 protein_coding -/- interior 17:81511495-81512092 597.0 Human
ACTG1/17:81511904-81511906-81512015-81512017--/- ACTG1 protein_coding -/- partial 17:81511904-81512015 111.0 Human
ACTG1/17:81511917-81511925-81512019-81512027--/- ACTG1 protein_coding -/- interior 17:81511917-81512019 102.0 Human
ACTG1/17:81512191-81512194-81512432-81512435--/- ACTG1 protein_coding -/- interior 17:81512194-81512435 241.0 Human
ACTN1/14:68979015-68979020-68979127-68979132--/- ACTN1 protein_coding -/- interior 14:68979015-68979127 112.0 Human
ACTN1/14:68979018-68979023-68979121-68979126--/- ACTN1 protein_coding -/- interior 14:68979018-68979121 103.0 Human