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Tissue: K562
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ACIN1/14:23059425-23059429-23059265-23059269-+/- ACIN1 protein_coding +/- antisense 14:23059425-23059265 160.0 Human
ACIN1/14:23080249-23080251-23080429-23080431--/- ACIN1 protein_coding -/- interior 14:23080249-23080429 180.0 Human
ACIN1/14:23080466-23080472-23080640-23080646--/- ACIN1 protein_coding -/- interior 14:23080472-23080646 174.0 Human
ACIN1/14:23080477-23080585--/- ACIN1 protein_coding -/- interior 14:23080477-23080585 108.0 Human
ACIN1/14:23080595-23080604-23080697-23080706--/- ACIN1 protein_coding -/- interior 14:23080595-23080697 102.0 Human
ACIN1/14:23080595-23080697--/- ACIN1 protein_coding -/- interior 14:23080595-23080697 102.0 Human
ACIN1/14:23080596-23080596-23080698-23080698--/- ACIN1 protein_coding -/- interior 14:23080596-23080698 102.0 Human
ACLY/17:41871685-41873962--/- ACLY protein_coding -/- interior 17:41871685-41873962 2277.0 Human
ACLY/17:41887612-41892412--/- ACLY protein_coding -/- interior 17:41887612-41892412 4800.0 Human
ACLY/17:41892273-41892278-41897834-41897839--/- ACLY protein_coding -/- canonical (exon-exon) 17:41892278-41897839 5561.0 Human