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Tissue: K562
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
AATF/17:36988716-36988718-36953199-36953201-+/+ AATF protein_coding +/+ interior 17:36988718-36953201 35517.0 Human
AATK/17:81120684-81120688-81120858-81120862--/- AATK protein_coding -/- interior 17:81120688-81120862 174.0 Human
ABCA12/2:215001559-215018134--/- ABCA12 protein_coding -/- canonical (exon-exon) 2:215001559-215018134 16575.0 Human
ABCA12/2:215025674-215026940--/- ABCA12 protein_coding -/- canonical (exon-exon) 2:215025674-215026940 1266.0 Human
ABCA3/16:2278304-2278304-2278458-2278458--/- ABCA3 protein_coding -/- partial 16:2278304-2278458 154.0 Human
ABCA3/16:2281028-2281033-2281223-2281228--/- ABCA3 protein_coding -/- partial 16:2281028-2281223 195.0 Human
ABCC4/13:95161180-95161186-95170620-95170626--/- ABCC4 protein_coding -/- interior 13:95161186-95170626 9440.0 Human
ABCF1/6:30590875-30590876-30590751-30590752-+/+ ABCF1 protein_coding +/+ interior 6:30590875-30590751 124.0 Human
ABCF1/6:30590877-30590882-30590753-30590758-+/+ ABCF1 protein_coding +/+ interior 6:30590877-30590753 124.0 Human
ABCF1/6:30590914-30590915-30590696-30590697-+/+ ABCF1 protein_coding +/+ interior 6:30590914-30590696 218.0 Human