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Tissue: K562
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
AARS1/16:70276482-70276483-70282781-70282782--/- AARS1 protein_coding -/- interior 16:70276483-70282782 6299.0 Human
AARS1/16:70277051-70277057-70282660-70282666--/- AARS1 protein_coding -/- interior 16:70277051-70282660 5609.0 Human
AATF/17:36948984-36948990-36949119-36949125--/+ AATF protein_coding -/+ antisense 17:36948984-36949119 135.0 Human
AATF/17:36953188-36953190-36953039-36953041-+/+ AATF protein_coding +/+ interior 17:36953188-36953039 149.0 Human
AATF/17:36953213-36953215-36953042-36953044-+/+ AATF protein_coding +/+ interior 17:36953213-36953042 171.0 Human
AATF/17:36953228-36953237-36953094-36953103-+/+ AATF protein_coding +/+ interior 17:36953237-36953103 134.0 Human
AATF/17:36953256-36953261-36953115-36953120-+/+ AATF protein_coding +/+ interior 17:36953256-36953115 141.0 Human
AATF/17:36953256-36953263-36953118-36953125-+/+ AATF protein_coding +/+ interior 17:36953256-36953118 138.0 Human
AATF/17:36953261-36953263-36953113-36953115-+/+ AATF protein_coding +/+ interior 17:36953261-36953113 148.0 Human
AATF/17:36953270-36953277-36953119-36953126-+/+ AATF protein_coding +/+ interior 17:36953270-36953119 151.0 Human