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Tissue: K562
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
AARS1/16:70258032-70259186--/- AARS1 protein_coding -/- canonical (exon-exon) 16:70258032-70259186 1154.0 Human
AARS1/16:70258247-70258247-70258979-70258979--/- AARS1 protein_coding -/- lariat 16:70258247-70258979 732.0 Human
AARS1/16:70258979-70262524--/- AARS1 protein_coding -/- canonical (exon-exon) 16:70258979-70262524 3545.0 Human
AARS1/16:70258981-70270342--/- AARS1 protein_coding -/- canonical (exon-exon) 16:70258981-70270342 11361.0 Human
AARS1/16:70261045-70262526--/- AARS1 protein_coding -/- canonical (exon-exon) 16:70261045-70262526 1481.0 Human
AARS1/16:70261192-70261193-70262343-70262344--/- AARS1 protein_coding -/- interior 16:70261193-70262344 1151.0 Human
AARS1/16:70262481-70262351-+/- AARS1 protein_coding +/- antisense 16:70262481-70262351 130.0 Human
AARS1/16:70265600-70267792--/- AARS1 protein_coding -/- interior 16:70265600-70267792 2192.0 Human
AARS1/16:70267661-70267662-70268382-70268383--/- AARS1 protein_coding -/- interior 16:70267661-70268382 721.0 Human
AARS1/16:70267808-70259000-+/- AARS1 protein_coding +/- antisense 16:70267808-70259000 8808.0 Human