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Tissue: A549
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
AARS1/16:70276510-70276517-70277060-70277067--/- AARS1 protein_coding -/- interior 16:70276510-70277060 550.0 Human
AATF/17:36949194-36949195-36949093-36949094-+/+ AATF protein_coding +/+ interior 17:36949194-36949093 101.0 Human
AATF/17:36949197-36949205-36949096-36949104-+/+ AATF protein_coding +/+ interior 17:36949197-36949096 101.0 Human
AATF/17:36953106-36953108-36952984-36952986-+/+ AATF protein_coding +/+ interior 17:36953106-36952984 122.0 Human
AATF/17:36953113-36953118-36952984-36952989-+/+ AATF protein_coding +/+ interior 17:36953113-36952984 129.0 Human
AATF/17:36953190-36953194-36953086-36953090-+/+ AATF protein_coding +/+ interior 17:36953194-36953090 104.0 Human
AATF/17:36953202-36953207-36953074-36953079-+/+ AATF protein_coding +/+ interior 17:36953202-36953074 128.0 Human
AATF/17:36953205-36953206-36953061-36953062-+/+ AATF protein_coding +/+ interior 17:36953205-36953061 144.0 Human
AATF/17:36953219-36953219-36952986-36952986-+/+ AATF protein_coding +/+ interior 17:36953219-36952986 233.0 Human
AATF/17:36953228-36953237-36953094-36953103-+/+ AATF protein_coding +/+ interior 17:36953237-36953103 134.0 Human