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Tissue: A549
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ABCC1/16:16009900-16009902-16007814-16007816-+/+ ABCC1 protein_coding +/+ canonical (exon-exon) 16:16009900-16007814 2086.0 Human
ABCC1/16:16016621-16016622-16007815-16007816-+/+ ABCC1 protein_coding +/+ canonical (exon-exon) 16:16016622-16007816 8806.0 Human
ABCC1/16:16044629-16044631-16044473-16044475-+/+ ABCC1 protein_coding +/+ interior 16:16044629-16044473 156.0 Human
ABCC1/16:16056294-16056295-16033107-16033108-+/+ ABCC1 protein_coding +/+ canonical (exon-exon) 16:16056294-16033107 23187.0 Human
ABCC1/16:16111510-16111516-16111408-16111414-+/+ ABCC1 protein_coding +/+ interior 16:16111510-16111408 102.0 Human
ABCC1/16:16114934-16114940-16111522-16111528-+/+ ABCC1 protein_coding +/+ interior 16:16114934-16111522 3412.0 Human
ABCC1/16:16115074-16115077-16076323-16076326-+/+ ABCC1 protein_coding +/+ canonical (exon-exon) 16:16115077-16076326 38751.0 Human
ABCC1/16:16122030-16122031-16115020-16115021-+/+ ABCC1 protein_coding +/+ interior 16:16122030-16115020 7010.0 Human
ABCC1/16:16122119-16122120-16121999-16122000-+/+ ABCC1 protein_coding +/+ interior 16:16122119-16121999 120.0 Human
ABCC1/16:16124821-16124831-16114997-16115007-+/+ ABCC1 protein_coding +/+ interior 16:16124821-16114997 9824.0 Human