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Tissue: A549
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ABCC1/16:16134497-16134499-16134382-16134384-+/+ ABCC1 protein_coding +/+ interior 16:16134497-16134382 115.0 Human
ABCC1/16:16136528-16136529-16134458-16134459-+/+ ABCC1 protein_coding +/+ interior 16:16136528-16134458 2070.0 Human
ABCC1/16:16141483-16141381-+/+ ABCC1 protein_coding +/+ interior 16:16141483-16141381 102.0 Human
ABCC1/16:16141493-16141498-16141358-16141363-+/+ ABCC1 protein_coding +/+ interior 16:16141493-16141358 135.0 Human
ABCC1/16:16141497-16141378-+/+ ABCC1 protein_coding +/+ interior 16:16141497-16141378 119.0 Human
ABCC1/16:16141497-16141498-16141378-16141379-+/+ ABCC1 protein_coding +/+ interior 16:16141497-16141378 119.0 Human
ABCC1/16:16141499-16141507-16141380-16141388-+/+ ABCC1 protein_coding +/+ interior 16:16141499-16141380 119.0 Human
ABCC1/16:16141543-16141548-16141428-16141433-+/+ ABCC1 protein_coding +/+ interior 16:16141543-16141428 115.0 Human
ABCC1/16:16141739-16141741-16141554-16141556-+/+ ABCC1 protein_coding +/+ interior 16:16141739-16141554 185.0 Human
ABCC1/16:16141745-16141749-16141576-16141580-+/+ ABCC1 protein_coding +/+ interior 16:16141749-16141580 169.0 Human