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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
GSTM5/1:113918959-113918960-113902534-113902535-+/- GSTM5 protein_coding +/- antisense 1:113918960-113902535 16425.0 Crab-eating macaque
DDX19B/20:59916999-59916999-59954159-59954159--/- DDX19B protein_coding -/- interior 20:59916999-59954159 37160.0 Crab-eating macaque
CCDC127::intergenic/6:305206-305208-348287-348289--/- CCDC127::intergenic protein_coding -/- intergenic 6:305208-348289 43081.0 Crab-eating macaque
GSTM5/1:113949061-113949064-113902731-113902734-+/- GSTM5 protein_coding +/- intergenic 1:113949064-113902734 46330.0 Crab-eating macaque
UBB/16:16159977-16159982-16159521-16159526-+/- UBB protein_coding +/- antisense 16:16159977-16159521 456.0 Crab-eating macaque
intergenic/8:142786293-142786313-142788270-142788290--/. intergenic Na -/. intergenic 8:142786313-142788290 1977.0 Crab-eating macaque
intergenic/8:142788270-142788290-142786293-142786313-+/. intergenic Na +/. intergenic 8:142788290-142786313 1977.0 Crab-eating macaque
intergenic/11:124263820-124263840-124264734-124264754--/. intergenic Na -/. intergenic 11:124263833-124264747 914.0 Crab-eating macaque
FAHD2A/13:469166-469168-446980-446982-+/+ FAHD2A protein_coding +/+ partial 13:469166-446980 22186.0 Crab-eating macaque
intergenic/11:124264734-124264754-124264050-124264070-+/. intergenic Na +/. intergenic 11:124264740-124264056 684.0 Crab-eating macaque