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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
6030443J06Rik/5:22951546-22951548-22951380-22951382-+/+ 6030443J06Rik lncRNA +/+ interior 5:22951546-22951380 166.0 Mouse
6330403K07Rik/11:70923017-70923021-70924254-70924258--/- 6330403K07Rik protein_coding -/- interior 11:70923017-70924254 1237.0 Mouse
6330403K07Rik/11:70923116-70923117-70923585-70923586--/- 6330403K07Rik protein_coding -/- interior 11:70923117-70923586 469.0 Mouse
6330403K07Rik/11:70923145-70923146-70923521-70923522--/- 6330403K07Rik protein_coding -/- interior 11:70923146-70923522 376.0 Mouse
6330403K07Rik/11:70923153-70923159-70923936-70923942--/- 6330403K07Rik protein_coding -/- interior 11:70923153-70923936 783.0 Mouse
6330403K07Rik/11:70923183-70923187-70923741-70923745--/- 6330403K07Rik protein_coding -/- interior 11:70923187-70923745 558.0 Mouse
6330403K07Rik/11:70923570-70923571-70923820-70923821--/- 6330403K07Rik protein_coding -/- interior 11:70923570-70923820 250.0 Mouse
6330403K07Rik/11:70923586-70923587-70924188-70924189--/- 6330403K07Rik protein_coding -/- interior 11:70923587-70924189 602.0 Mouse
6330403K07Rik/11:70923594-70923599-70924238-70924243--/- 6330403K07Rik protein_coding -/- interior 11:70923594-70924238 644.0 Mouse
6330403K07Rik/11:70923651-70923652-70924236-70924237--/- 6330403K07Rik protein_coding -/- interior 11:70923652-70924237 585.0 Mouse