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Tissue: A375
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ABR/17:1005733-1005734-1005895-1005896--/- ABR protein_coding -/- partial 17:1005733-1005895 162.0 Human
ABTB3/12:107598804-107598810-107598516-107598522-+/+ ABTB3 protein_coding +/+ interior 12:107598804-107598516 288.0 Human
ACACA/17:37248008-37248010-37253034-37253036--/- ACACA protein_coding -/- canonical (exon-exon) 17:37248010-37253036 5026.0 Human
ACADVL/17:7221928-7221928-7221704-7221704-+/+ ACADVL protein_coding +/+ interior 17:7221928-7221704 224.0 Human
ACBD3/1:226152349-226152350-226152559-226152560--/- ACBD3 protein_coding -/- interior 1:226152349-226152559 210.0 Human
ACBD6/1:180502394-180502395-180502535-180502536--/- ACBD6 protein_coding -/- interior 1:180502394-180502535 141.0 Human
ACIN1/14:23059172-23059173-23059277-23059278--/- ACIN1 protein_coding -/- interior 14:23059172-23059277 105.0 Human
ACIN1/14:23059291-23059292-23059414-23059415--/- ACIN1 protein_coding -/- interior 14:23059292-23059415 123.0 Human
ACIN1/14:23059325-23059328-23061456-23061459--/- ACIN1 protein_coding -/- interior 14:23059325-23061456 2131.0 Human
ACIN1/14:23080517-23080523-23080679-23080685--/- ACIN1 protein_coding -/- interior 14:23080517-23080679 162.0 Human