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Tissue: A375
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ACSL3/2:222930790-222930791-222930619-222930620-+/+ ACSL3 protein_coding +/+ partial 2:222930790-222930619 171.0 Human
ACSL3/2:222932345-222932350-222932020-222932025-+/+ ACSL3 protein_coding +/+ interior 2:222932345-222932020 325.0 Human
ACTB/7:5527303-5527307-5527791-5527795--/- ACTB protein_coding -/- interior 7:5527303-5527791 488.0 Human
ACTB/7:5528526-5528530-5529196-5529200--/- ACTB protein_coding -/- interior 7:5528526-5529196 670.0 Human
ACTB/7:5528542-5528546-5529212-5529216--/- ACTB protein_coding -/- interior 7:5528542-5529212 670.0 Human
ACTB/7:5528752-5528752-5529160-5529160--/- ACTB protein_coding -/- lariat 7:5528752-5529160 408.0 Human
ACTG1/17:81510392-81510397-81510524-81510529--/- ACTG1 protein_coding -/- partial 17:81510392-81510524 132.0 Human
ACTG1/17:81511249-81511254-81512038-81512043--/- ACTG1 protein_coding -/- interior 17:81511254-81512043 789.0 Human
ACTG1/17:81511469-81511471-81511963-81511965--/- ACTG1 protein_coding -/- interior 17:81511469-81511963 494.0 Human
ACTG1/17:81511917-81511925-81512019-81512027--/- ACTG1 protein_coding -/- interior 17:81511917-81512019 102.0 Human