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Tissue: A375
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ACTN4/19:38725796-38725802-38724283-38724289-+/+ ACTN4 protein_coding +/+ interior 19:38725796-38724283 1513.0 Human
ACTN4/19:38729716-38729723-38729488-38729495-+/+ ACTN4 protein_coding +/+ interior 19:38729716-38729488 228.0 Human
ACTN4/19:38729832-38729835-38729604-38729607-+/+ ACTN4 protein_coding +/+ interior 19:38729832-38729604 228.0 Human
ACTN4/19:38729895-38729901-38729631-38729637-+/+ ACTN4 protein_coding +/+ interior 19:38729901-38729637 264.0 Human
ACTN4/19:38730466-38730467-38730349-38730350-+/+ ACTN4 protein_coding +/+ interior 19:38730466-38730349 117.0 Human
ACTR2/2:65265176-65265177-65239852-65239853-+/+ ACTR2 protein_coding +/+ canonical (exon-exon) 2:65265177-65239853 25324.0 Human
ACTR8/3:53867608-53867610-53877340-53877342--/- ACTR8 protein_coding -/- interior 3:53867608-53877340 9732.0 Human
ADAM10/15:58596869-58596870-58597034-58597035--/- ADAM10 protein_coding -/- interior 15:58596869-58597034 165.0 Human
ADAM10/15:58749480-58749482-58749733-58749735--/- ADAM10 protein_coding -/- partial 15:58749482-58749735 253.0 Human
ADAM17/2:9509982-9509983-9527958-9527959--/- ADAM17 protein_coding -/- interior 2:9509982-9527958 17976.0 Human