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Tissue: A375
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ADPGK/15:72756246-72756249-72756443-72756446--/- ADPGK protein_coding -/- partial 15:72756249-72756446 197.0 Human
ADPRS/1:36091211-36091217-36089154-36089160-+/+ ADPRS protein_coding +/+ interior 1:36091211-36089154 2057.0 Human
ADPRS/1:36093752-36093758-36093650-36093656-+/+ ADPRS protein_coding +/+ interior 1:36093752-36093650 102.0 Human
ADRB2/5:148826868-148826870-148826740-148826742-+/+ ADRB2 protein_coding +/+ interior 5:148826868-148826740 128.0 Human
ADRM1/20:62308153-62308155-62307694-62307696-+/+ ADRM1 protein_coding +/+ interior 20:62308153-62307694 459.0 Human
ADRM1/20:62308171-62308176-62307748-62307753-+/+ ADRM1 protein_coding +/+ interior 20:62308171-62307748 423.0 Human
ADSS2/1:244417627-244417628-244437768-244437769--/- ADSS2 protein_coding -/- canonical (exon-exon) 1:244417627-244437768 20141.0 Human
AFAP1/4:7760951-7760954-7761110-7761113--/- AFAP1 protein_coding -/- interior 4:7760951-7761110 159.0 Human
AFAP1/4:7762107-7762112-7762273-7762278--/- AFAP1 protein_coding -/- interior 4:7762107-7762273 166.0 Human
AFAP1/4:7763633-7763634-7763765-7763766--/- AFAP1 protein_coding -/- interior 4:7763633-7763765 132.0 Human