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Tissue: A375
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
AFAP1/4:7798268-7798280-7798408-7798420--/- AFAP1 protein_coding -/- interior 4:7798280-7798420 140.0 Human
AFG3L2/18:12353008-12353010-12356835-12356837--/- AFG3L2 protein_coding -/- interior 18:12353008-12356835 3827.0 Human
AGAP3/7:151120717-151120721-151120076-151120080-+/+ AGAP3 protein_coding +/+ interior 7:151120717-151120076 641.0 Human
AGK/7:141555958-141555966-141555624-141555632-+/+ AGK protein_coding +/+ interior 7:141555966-141555632 334.0 Human
AGMO/7:15473854-15473858-15474060-15474064--/- AGMO protein_coding -/- interior 7:15473854-15474060 206.0 Human
AGO1/1:35917728-35917731-35901948-35901951-+/+ AGO1 protein_coding +/+ canonical (exon-exon) 1:35917731-35901951 15780.0 Human
AGO2/8:140525837-140525841-140525978-140525982--/- AGO2 protein_coding -/- interior 8:140525837-140525978 141.0 Human
AGO2/8:140617528-140617532-140618192-140618196--/- AGO2 protein_coding -/- interior 8:140617532-140618196 664.0 Human
AGO2/8:140622287-140622293-140623217-140623223--/- AGO2 protein_coding -/- interior 8:140622287-140623217 930.0 Human
AGPAT1/6:32168613-32168615-32168932-32168934--/- AGPAT1 protein_coding -/- interior 6:32168613-32168932 319.0 Human