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Tissue: HT-29
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ACTN4/19:38706021-38706021-38705019-38705019-+/+ ACTN4 protein_coding +/+ lariat 19:38706021-38705019 1002.0 Human
ACTN4/19:38706022-38706022-38705020-38705020-+/+ ACTN4 protein_coding +/+ lariat 19:38706022-38705020 1002.0 Human
ACTN4/19:38719581-38719582-38719252-38719253-+/+ ACTN4 protein_coding +/+ interior 19:38719581-38719252 329.0 Human
ACTN4/19:38724332-38724337-38724016-38724021-+/+ ACTN4 protein_coding +/+ interior 19:38724332-38724016 316.0 Human
ACTN4/19:38725796-38725802-38724283-38724289-+/+ ACTN4 protein_coding +/+ interior 19:38725796-38724283 1513.0 Human
ACTN4/19:38725880-38725884-38724285-38724289-+/+ ACTN4 protein_coding +/+ interior 19:38725880-38724285 1595.0 Human
ACTN4/19:38727825-38727826-38727101-38727102-+/+ ACTN4 protein_coding +/+ lariat 19:38727826-38727102 724.0 Human
ACTN4/19:38729475-38729480-38729356-38729361-+/+ ACTN4 protein_coding +/+ interior 19:38729480-38729361 119.0 Human
ACTN4/19:38729716-38729723-38729488-38729495-+/+ ACTN4 protein_coding +/+ interior 19:38729716-38729488 228.0 Human
ACTN4/19:38729742-38729743-38729476-38729477-+/+ ACTN4 protein_coding +/+ interior 19:38729742-38729476 266.0 Human