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Tissue: HT-29
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circRNA ID Gene Gene Type Strand (circRNA/Gene)
circRNA Type i

The back-fusion junctions (BFJs) of circRNAs from genic regions may have three possible positions relative to the nearest exon-intron boundaries of their cognate linear transcripts, giving rise to three circRNA subtypes:

(1) canonical (or completely boundary) circRNAs with both BFJs aligning to exon-intron boundaries;

(2) half interior (or half boundary) circRNAs with one, but not both, of the BFJs aligning to exon-intron boundaries;

(3) complete interior (or non-boundary) circRNAs with both junctions appearing inside of exons or introns.

Lariats are byproducts of splicing and can be regarded as variants of canonical circRNAs; for clarity, we list lariats separately here.

Intergenic circRNAs, derived from intergenic regions that often encode poorly annotated noncoding transcripts, can be considered a new distinct subtype of their own.

We collectively refer to complete interior, half interior, and intergenic circRNAs as noncanonical circRNAs (nc-circRNAs) to distinguish them from canonical circRNAs (c-circRNAs).

CircRNA Types Diagram
Position Length Species
ACSS1/20:25020014-25020016-25023646-25023648--/- ACSS1 protein_coding -/- interior 20:25020014-25023646 3632.0 Human
ACTB/7:5527480-5527482-5527753-5527755--/- ACTB protein_coding -/- interior 7:5527480-5527753 273.0 Human
ACTB/7:5527488-5527490-5528179-5528181--/- ACTB protein_coding -/- interior 7:5527490-5528181 691.0 Human
ACTB/7:5528414-5528419-5529188-5529193--/- ACTB protein_coding -/- interior 7:5528419-5529193 774.0 Human
ACTB/7:5528744-5528745-5529161-5529162--/- ACTB protein_coding -/- lariat 7:5528744-5529161 417.0 Human
ACTB/7:5528975-5528976-5529130-5529131--/- ACTB protein_coding -/- interior 7:5528975-5529130 155.0 Human
ACTB/7:5529207-5529207-5529357-5529357--/- ACTB protein_coding -/- interior 7:5529207-5529357 150.0 Human
ACTB/7:5529540-5529545-5529661-5529666--/- ACTB protein_coding -/- partial 7:5529540-5529661 121.0 Human
ACTG1/17:81510181-81510181-81510543-81510543--/- ACTG1 protein_coding -/- interior 17:81510181-81510543 362.0 Human
ACTG1/17:81510191-81510192-81510356-81510357--/- ACTG1 protein_coding -/- interior 17:81510191-81510356 165.0 Human